I don’t drill in the traditional sense of a drill cycle in Fusion360. When I want to make holes, I use the bore CAM path, which is known as interpolating. This is not as accurate as drilling or reaming, but once you get it dialed in, it works fine, especially if you just need clearance and not something like slip fit, etc…
They have a drilling function it looks like. I would use the peck drilling feature to clear chips, give it some lube/coolant. As far as sppeds and feeds I can’t really help you other than to suggest downloading g-wizard, it has been a life saver.
So this is where it gets a bit above my knowledge level. You have a million options. It really all boils down to how accurate you need the hole to be, what coolant options you have and probably 6 other variables I am not thinking of right now. I have had really good luck with Datron tooling, it is a bit more expensive but lasts a long time and they are engineered for higher RPM spindles. You can see the drill options here - Drill - DATRON CNC Milling Tools
Good luck and please let me know how it goes, been thinking of switching to drilling for a while but have not jumped in yet.